Zerodol-SP Tablet: Uses, Side Effects, Dosage, Composition & Price
Zerodol-SP is a prescription combination tablet containing aceclofenac 100 mg, paracetamol 325 mg and serratiopeptidase 15 mg. It is commonly prescribed for selected pain, inflammation and swelling.
What Is Zerodol-SP? Composition
Zerodol-SP combines an NSAID, a pain-relieving medicine and serratiopeptidase.
Aceclofenac 100 mg
An NSAID used to reduce pain and inflammation.
Paracetamol 325 mg
Provides pain-relieving and fever-reducing effects.
Serratiopeptidase 15 mg
An enzyme included in the combination and intended to help with inflammatory swelling.
Zerodol-SP Uses
Doctors may prescribe it for selected conditions involving pain, inflammation or swelling:
Muscle & Joint Pain
May be used for acute musculoskeletal pain when an anti-inflammatory medicine is appropriate.
Arthritis
May provide symptomatic relief in selected inflammatory joint conditions.
Dental Pain
May be prescribed for selected acute dental pain, while the cause still needs dental treatment.
Injury & Postoperative Pain
May be prescribed for selected injury-related or postoperative pain and swelling.
Zerodol-SP Dosage & How to Take It
The dose and duration should be decided by the prescribing doctor. Online dosage information is not a personal prescription.
- Take exactly as prescribed.
- Swallow with water.
- Follow instructions about taking it with food.
- Do not increase the dose because pain is severe.
- Do not combine with another paracetamol-containing medicine unless advised.
- Do not double a missed dose.
Zerodol-SP Side Effects
- Nausea
- Vomiting
- Indigestion
- Heartburn
- Stomach pain
- Diarrhoea
- Dizziness
- Drowsiness
- Loss of appetite
When to get urgent help
Seek medical attention for black or bloody stools, vomiting blood, severe abdominal pain, breathing difficulty, facial/throat swelling, severe rash, jaundice, unusual bleeding, fainting or markedly reduced urine output.
Precautions, Pregnancy, Alcohol & Interactions
Extra caution
Tell your doctor about ulcers, kidney/liver disease, heart disease, high blood pressure, NSAID allergy, bleeding problems or multiple medicines.
Pregnancy
Do not take during pregnancy unless specifically prescribed. NSAIDs require particular caution during pregnancy.
Alcohol & interactions
Avoid alcohol. Tell your doctor about blood thinners, other NSAIDs, aspirin, steroids, diuretics, methotrexate, lithium, digoxin and other medicines.
Zerodol-SP for Tooth Pain, Back Pain & Fever
Tooth Pain
It may be prescribed for selected acute dental pain but does not treat the underlying dental cause.
Back Pain
It may be used for selected acute musculoskeletal pain. Persistent or severe pain needs assessment.
Fever
It contains paracetamol, but persistent or high fever needs evaluation for its cause.
Zerodol-SP vs Zerodol-P
| Feature | Zerodol-P | Zerodol-SP |
|---|---|---|
| Aceclofenac | Yes | Yes |
| Paracetamol | Yes | Yes |
| Serratiopeptidase | No | Yes |
| Best choice | Depends on diagnosis and medical advice | |
Zerodol-SP Price in India 2026
Price varies by pack size, pharmacy, location, discounts and market availability. Check the latest printed MRP or current licensed-pharmacy price rather than relying on a permanent online price.
How Does Zerodol-SP Work?
Zerodol-SP combines three ingredients that act in different ways. Aceclofenac is an NSAID that reduces substances involved in pain and inflammation. Paracetamol helps reduce pain and fever. Serratiopeptidase is included in the combination for its proposed role in reducing inflammatory swelling; however, evidence for serratiopeptidase can vary by condition and it should not be considered a guaranteed treatment.
Because the tablet contains more than one active ingredient, taking additional painkillers without checking their ingredients can increase the risk of side effects or accidental overdose.
When Is Zerodol-SP Usually Prescribed?
A doctor may consider Zerodol-SP when a patient has pain together with inflammation or swelling and a combination medicine is appropriate. The exact reason for prescribing it depends on the diagnosis.
After an Injury
For selected soft-tissue or musculoskeletal injuries where pain and inflammation are present.
After Certain Procedures
It may be prescribed for selected postoperative or dental pain and swelling. The underlying condition still needs appropriate treatment.
Joint Inflammation
It may provide symptomatic relief in selected arthritis or inflammatory joint conditions.
Acute Musculoskeletal Pain
It may be considered for certain short-term muscle, joint or back pain when an NSAID is suitable.
Who Should Not Take Zerodol-SP Without Medical Advice?
Do not start Zerodol-SP on your own if you have a history of serious reaction to aceclofenac, other NSAIDs or aspirin, significant stomach ulcer or bleeding, serious kidney or liver disease, or another condition for which NSAIDs may be unsuitable.
Before a doctor prescribes it, mention all medicines and supplements you take. This is especially important if you use medicines that affect bleeding, blood pressure, kidney function or liver function.
What Should You Avoid While Taking Zerodol-SP?
- Avoid taking another NSAID such as diclofenac, ibuprofen, naproxen or aspirin for pain unless your doctor says it is appropriate.
- Check cold, flu and headache medicines for paracetamol before taking them together.
- Avoid alcohol unless your healthcare professional specifically advises otherwise.
- Do not drive or operate machinery if the medicine makes you dizzy or drowsy.
- Do not use leftover tablets from an earlier illness for a new type of pain without medical advice.
Zerodol-SP for Common Types of Pain: What Patients Want to Know
Can Zerodol-SP be used for severe toothache?
It may provide temporary pain relief when prescribed, but severe toothache can be caused by decay, infection or an abscess. Pain relief does not remove the dental cause, so dental assessment may still be necessary.
Can Zerodol-SP help with back pain?
It may help selected acute musculoskeletal back pain when an NSAID is appropriate. Back pain with weakness, numbness, bladder or bowel changes, fever or major injury needs prompt medical assessment.
Is Zerodol-SP useful for knee or joint pain?
It can provide symptomatic relief in some joint conditions, but persistent joint pain needs evaluation to identify the cause and appropriate long-term treatment.
Can Zerodol-SP reduce swelling?
Its ingredients are intended to help reduce pain and inflammatory symptoms. Persistent or unexplained swelling should be evaluated rather than repeatedly treated with painkillers.
What Happens If You Take Zerodol-SP for Too Long?
Longer or repeated use of NSAID-containing medicines can increase the risk of stomach ulcers or bleeding, kidney problems, fluid retention and other complications in susceptible people. Paracetamol can also cause serious liver injury when taken in excessive amounts or combined with other paracetamol-containing products.
For this reason, repeated use should be reviewed by a doctor rather than continued automatically whenever pain returns.
How to Use Zerodol-SP More Safely: A Simple Checklist
| Before taking it | Check with a doctor/pharmacist |
|---|---|
| Know why it was prescribed | History of ulcer or GI bleeding |
| Check all active ingredients | Kidney or liver disease |
| Follow the prescribed dose | Pregnancy or breastfeeding |
| Tell them about all medicines | Blood thinners or multiple medicines |
People Also Ask: Zerodol-SP
Is Zerodol-SP a painkiller?
Yes. It is a prescription combination medicine used for pain and inflammation.
Is Zerodol-SP an antibiotic or steroid?
No. Zerodol-SP is neither an antibiotic nor a corticosteroid.
Can Zerodol-SP be used for tooth pain?
It may be prescribed for selected acute dental pain, but it does not treat the underlying cause such as tooth decay or an abscess.
Can Zerodol-SP be used for back pain?
It may help selected acute musculoskeletal back pain when an NSAID is appropriate. Persistent or severe back pain needs medical evaluation.
Can I take Zerodol-SP with paracetamol?
Do not add another paracetamol-containing medicine unless a doctor or pharmacist confirms it is safe, because Zerodol-SP already contains paracetamol.
Can I take Zerodol-SP with ibuprofen or diclofenac?
Do not combine NSAIDs such as ibuprofen or diclofenac with Zerodol-SP unless specifically advised by a healthcare professional, as this can increase adverse-effect risk.
Can Zerodol-SP be taken during pregnancy?
Do not take it during pregnancy unless specifically prescribed by your doctor. NSAIDs require particular caution during pregnancy.
Can I take Zerodol-SP with alcohol?
It is best to avoid alcohol while taking it because of increased stomach and liver-related safety concerns.
Is Zerodol-SP safe for kidney patients?
Not necessarily. NSAIDs can affect kidney function, so people with kidney disease should use it only under medical advice.
Can Zerodol-SP cause acidity or stomach pain?
Yes. Indigestion, heartburn and stomach pain can occur. Black stools, vomiting blood or severe abdominal pain need urgent medical attention.
How long can I take Zerodol-SP?
Use it only for the duration prescribed. Repeated or prolonged use should be reviewed by a doctor.
What should I do if Zerodol-SP does not relieve my pain?
Do not increase the dose yourself. If pain is severe, persistent or worsening, contact your doctor for reassessment.
Need Medical Advice About Pain or a Medicine?
For persistent, severe or unexplained pain, consult a qualified doctor rather than repeatedly self-medicating.
Medical disclaimer: This page is for general education and does not replace advice from a qualified doctor or pharmacist. Do not start, stop or change prescription medicines without professional advice.
Last reviewed: October 2026